1 box- "Sulfadiazine Tablets, U.S.P."
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1 box- "Sulfadiazine Tablets, U.S.P."

Historical artifact -- Box;Medicine container

Identifier:
1992.94.20
Description
1 cardboard box-
Contains one glass medication bottle of Sulfadiazine tablets. The box reads, "LL 6505-889-3483, 500 Tablets, Sulfadiazine Tablets, U.S.P., 0.5 Gm. (7 1/2 Gr.)"

"Indications: Sulfadiazine is used in the prevention and treatment of sulfonamide susceptible infections; as, bacterial pneumonias, large boils, carbuncles, cellulitis, meningococcal meningitis, streptococcal infections, bacilliary dysentery and gonorrhea."
"Usual dosage: Adults: Initial-4 Gm. Maintenance-1 Gm. Every four to six hours until temperature has been normal for three to seven days. Children: initial - 100 to 150mg. per kg. of body weight every six hours day and night until temperature has been normal for two to five days." 
"Free Sulfadiazine concentration of blood should be maintained at 5 to 10mg. per 100 cc., Adequate intake of fluids to provide adult urinary output of at least one liter per 24 hours must be maintained. Alkalization of urine helps increase sulfonamide solubility." 
"Side effects: If signs of hypersensitivity; such as, rash, nausea, vomiting, urticaria and blood dyscrasias occur, the drug should be discontinued and fluids forced."
"Toxicity: Patient should be closely observed by physician. Blood and urine should be examined frequently. if volume of urine is low, fluids should be forced to avoid impaired renal function."
"Caution: Federal law prohibits dispensing without prescription. Keep this and All Medicines Out of Reach of Children. Lot No. 434, Success Chemical CO., Inc. Brooklyn, New York."
Content Date:
1960s

Related person
Department of Defense (references)
Related place
Rangely (references)